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General
Potential Adverse Effects of Psychotropic Medications (with adverse effect handout for patients)
Cardiovascular Risk Screening Form
How common are side effects of antidepressants?
Side effects: what’s the big deal?
Side Effects: Test Your Knowledge
How to assess persons who are “sensitive to medications.”
How to manage a person who is “sensitive to medications”
Dose reduction to manage adverse effects
Knowledge is power: Effective strategies for educating patients about potential adverse effects
Akathisia
Antidepressant discontinuation (withdrawal)
Antidepressant discontinuation (withdrawal): Introduction
Antidepressant discontinuation (withdrawal): Risk factors
Antidepressant discontinuation (withdrawal): Clinical features
Antidepressant discontinuation (withdrawal): Management
Antidepressant discontinuation and “brain zaps”
Bleeding
Who is at higher risk of bleeding with antidepressants?
Antidepressants and bleeding: When and what to ask?
Antidepressants and risk of stroke
Bruxism
Cognitive impairment
Diarrhea
Dizziness (Orthostatic hypotension)
Dry Mouth (Xerostomia)
Edema
Excessive sweating (Hyperhidrosis)
Glaucoma
Hair loss (Alopecia)
Hyperparathyroidism
Lithium induced hyperparathyroidism
How to screen for lithium-induced hyperparathyroidism
How to calculate corrected serum calcium
Hyperprolactinemia
Hypersalivation (Sialorrhea)
Clozapine-induced hypersalivation (sialorrhea)
Clozapine-induced hypersalivation (sialorrhea): Treatment
Hyponatremia
Insomnia
Liver damage
Antidepressants can injure the liver, some more than others
Disulfiram and liver toxicity
When and how often should hepatic function tests be done in patients on disulfiram?
Loss of appetite (Anorexia)
Myocarditis
Nausea
Medication-induced nausea: Level 1 (basic) strategies for prevention and management
Medication-induced nausea: Level 2 strategies for management
Pancreatitis
Parkinsonism
Pharmacogenomics of side effects
Serotonin transporter promoter region
Serotonin transporter linked polymorphic region (5-HTTLPR)
5-HTTLPR and efficacy of antidepressants
5-HTTLPR and adverse effects of antidepressants
5-HTTLPR and antidepressant-induced mania
Serotonergic receptors
Serotonin 2A receptor gene (HTR2A) polymorphisms and adverse effects
HTR2C polymorphisms and medication-induced weight gain
Blood-brain barrier/ P-glycoprotein
Cytochrome P450 enzymes
HLA gene testing
Melanocortin 4 receptor (MC4R)
Commercially-available pharmacogenomic tests
Polyuria/ Diabetes Insipidus
Lithium-induced polyuria and diabetes insipidus
Lithium-induced polyuria and diabetes insipidus: Evaluation
Lithium-induced polyuria and diabetes insipidus: Treatment
QT Prolongation
Antipsychotics and QTc prolongation
Antibiotics, antipsychotics, and QTc prolongation
Doesn’t escitalopram cause QTc prolongation?
How to look up whether a drug can cause QTc prolongation or torsades
Three SSRIs that may cause QT prolongation
Warning: Hydroxyzine (Vistaril, Atarax) can be dangerous
Seizures
Antidepressants and seizures
Bupropion and seizures: the facts and the myths
What factors can increase the risk of seizures with bupropion?
Key information about seizures with clozapine
Transcranial Magnetic Stimulation (TMS): Risk of seizures
Sexual adverse effects
Sexual dysfunction
Management of sexual dysfunction: Interview with Anita Clayton, MD
Trazodone and priapism
Arizona Sexual Experiences Scale (ASEX)
An introduction to the Changes in Sexual Functioning Questionnaire (CSFQ)
How to administer, score, and interpret the Changes in Sexual Functioning Questionnaire (CSFQ)
Which laboratory tests in men with erectile dysfunction?
How to reduce the risk of erectile dysfunction
Which PDE-5 inhibitor for erectile dysfunction?
Beta blockers can worsen or improve erectile dysfunction
Skin reactions
Acne is a potential side effect of lithium
Rash, irritation, or itching with transdermal patches
How common are benign and serious rashes with lamotrigine?
Dermatological precautions when starting lamotrigine
Restarting lamotrigine
Warning-this could happen if we are not careful (Restarting lamotrigine)
Is it a benign or dangerous skin rash?
Non-drug causes of Stevens-Johnson Syndrome (SJS)/Toxic Epidermal Necrolysis (TEN)
Do past infections increase the risk of Stevens-Johnson Syndrome (SJS) / Toxic Epidermal Necrolysis (TEN)?
Tardive dyskinesia
Management of tardive dyskinesia: First-line options
Management of tardive dyskinesia: Second-line options
Comparing the VMAT2 inhibitors
Valbenazine (Ingrezza®) and VMAT2
An Expert answers YOUR questions about tardive dyskinesia
Is TD less likely with second-generation (“atypical”) antipsychotics?
Valbenazine (Ingrezza®): Basic information
Deutetrabenazine (Austedo®): Basic Information
Abnormal Involuntary Movement Scale
Abnormal Involuntary Movement Scale (AIMS): Examination procedure
Abnormal Involuntary Movement Scale (AIMS): Scoring instructions
Antidepressant-induced tardive dyskinesia
Tremors
Medication-induced tremors: An overview
How to examine a person with tremors
How to monitor change in the severity of a tremor
Lithium-induced benign tremor: Introduction
Lithium-induced benign tremor: Evaluation
Lithium-induced benign tremor: Treatment
Vitamin B6 for lithium-induced benign tremor?
Weight gain/Metabolic adverse effects
Do adolescents have more metabolic side effects with second-generation antipsychotics?
Monitoring for metabolic side effects in children and adolescents on a second-generation (atypical) antipsychotic
Does weight gain with second-generation (atypical) antipsychotics plateau after the first few months?
Metformin to prevent or treat metabolic adverse effects due to antipsychotics
Who is more likely to benefit from metformin for management of metabolic adverse effects?
Potential adverse effects of metformin
Tips on prescribing metformin
Can we use topiramate to treat medication-induced weight gain?
Metformin and topiramate for metabolic adverse effects?
Can melatonin increase blood sugar?