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Metformin AND topiramate for metabolic adverse effects?

Metformin and topiramate are two of the leading pharmacological options for treating metabolic syndrome associated with second-generation antipsychotic medications. Can they also be used together? Is the combination more effective? As of February 2018, I am unaware of any study comparing the combination of metformin and topiramate to either of these medications alone. But, this may…

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