What to do if a patient develops thrombocytopenia during treatment with valproate

This article was first published on March 4, 2024. It was last reviewed, updated, or edited on March 5, 2024. One of my outpatients with bipolar disorder had complete remission from mood episodes after being treated with divalproex (Depakote® ER). But, many months later, the family contacted me due to concern about a low platelet…