Phentermine (US brand name Adipex-P®, Lomaira™, and generic) is a sympathomimetic amine anorectic. Here is basic information about this medication.
FDA-approved indications
Short-term adjunct (a few weeks) in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index greater than or equal to 30 kg/m2 or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia)
Dosage
1. Adipex-P®
Usual dose is one tablet (37.5 mg) daily administered before breakfast or 1 to 2 hours after breakfast for appetite control
Dosage should be individualized to obtain an adequate response with the lowest effective dose. Some patients may need to be prescribed half tablet (18.75 mg) once daily while others may need half tablet (18.75 mg) twice daily.)
2. Lomaira™
Usual dose is 8 mg, three times daily, 30 minutes before meals. Tablet is scored to allow administration of one half of the usual dosage for patients not requiring the full dose.
Administration instructions
Phentermine is not recommended for children 16 years or younger.
Should not be prescribed late in the evening because of possibility of resulting insomnia
Dosage forms and strengths
1. Capsules (Adipex-P® and generic): 37.5 mg phentermine hydrochloride (equivalent to 30 mg phentermine base).
Also available as 15 mg and 30 mg (generic only) capsules
2. Tablets (Adipex-P® and generic): 37.5 mg phentermine hydrochloride (equivalent to 30 mg phentermine base),
3. Orally disintegrating tablets (generic only): 15 mg, 30 mg, and 37.5 mg
4. Low-dose scored tablets (Lomaira™ and generic): 8 mg phentermine hydrochloride (equivalent to 6.4 mg phentermine base)
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
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References
Prescribing Information for phentermine (Adipex-P®)
Prescribing Information for phentermine (Lomaira™)
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