Edema is a potential adverse effect of hydrazine MAO inhibitors like phenelzine and isocarboxazid. It has been known for a long time (e.g., Dunleavy, 1977). I have long used the mnemonic Oh WISE for some of the common side effects of MAOI. It stands for Orthostatic Hypotension, Weight gain, Insomnia, Sexual dysfunction, and Edema. What…