How to manage patients with increased bruising on a serotonin reuptake inhibitor

Question from a Member: I have a patient who developed significant bruising on sertraline…She has had significant benefit from sertraline. If the antidepressant can be changed 1.  Is a serotonergic antidepressant really essential? If bupropion can be used, that would be best. 2. it may be best to avoid those with a particularly high affinity for the…