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Clozapine-induced myocarditis or cardiomyopathy

Agranulocytosis is not the only medically serious potential adverse effect of clozapine. There are three other important ones. It can also cause intestinal ileus, seizures, and myocarditis. Mnemonic for the four: SIAM It is absolutely essential that if we ever prescribe clozapine—or even if we don’t prescribe clozapine ourselves but may see patients who are on clozapine—we…

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