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Drug interaction search (checker) tools
Drug interaction search (checker) tools: Free options
Drug interaction search (checker) tools: Paid options
Levels of seriousness in drug interaction search results
Video: How to do efficient drug interaction searches to quickly identify the important ones
Clinical example: Why we should ALWAYS do a quick drug interaction search
Who’s job is it to check for drug interactions?
COVID-19 drug interaction checker
How to check for drug interactions with an herbal product like ashwagandha
How to easily search for drug interactions with cannabidiol
Cytochrome P450 interactions
Cytochrome P450 system and psychiatric medications: An introduction and important tips
Cytochrome P450 3A4: Substrates, inhibitors, and inducers
What the FDA’s “Table of Pharmacogenetic Associations” says about psychotropic medications
Pharmacogenetic testing in the office: Cytochrome P450 enzymes
The Flockhart P450 Drug Interaction Table: Full table (Link to external site)
Supplement to Flockhart table
Antidepressants with much fewer P450 drug interactions
Doxepin and cytochrome P450 drug interactions
One exit door or many?
Cytochrome P450 drug interactions with benzodiazepines
Drug interactions with ADHD medications
Important interactions when using two medications for ADHD
Vitamin C if on a stimulant?
Be careful if a person is on both a stimulant and an antipsychotic
What could happen when changing from an antipsychotic to a stimulant?
Can a dopamine agonist (pramipexole, ropinirole) and a stimulant be combined?
Ketogenic diet and amphetamines
When prescribing an amphetamine, warn patients about anti-acid medications
Order genetic testing for a patient on atomoxetine?
Seizure risk if atomoxetine and bupropion are used together?
Drug interactions with antidepressant medications
Antidepressants with much fewer P450 drug interactions
Doxepin and cytochrome P450 drug interactions
Drug interactions with antipsychotic medications
What could happen when changing from an antipsychotic to a stimulant?
Be careful if a person is on both a stimulant and an antipsychotic
Drug interactions with COVID-19 medications
COVID-19 drug interaction checker
Nirmatrelvir-ritonavir (Paxlovid™): Drug interactions with psychiatric medications
Can patients on lurasidone take nirmatrelvir + ritonavir (Paxlovid®)?
Drug interactions with caffeine
Caffeine can significantly change serum clozapine levels
Interactions that can significantly affect caffeine metabolism
Drug interactions with cannabinoids
Drug interactions with cardiovascular medications
Lithium and antihypertensives: Be careful!
Direct-acting oral anticoagulants (DOACs) and antidepressants
Very important drug interactions between warfarin and psychotropic medications
Drug interactions with food and beverages
Grapefruit or its juice can interact with psychotropic medications
Ketogenic diet and amphetamines
Ketogenic diet and topiramate
Ketogenic diet and valproate
Vitamin C if on a stimulant?
Drug interactions with herbs and supplements
Interactions between herbal and psychotropic medications
How to check for drug interactions with an herbal product like ashwagandha
Biotin can interfere with many laboratory tests—and lead to serious misdiagnosis
Drug interactions with lithium
Drug interactions with monoamine oxidase inhibitors (MAOIs)
MAO inhibitors and other medications
MAO Inhibitors and other medications (patient handout) (link to the handouts page)
Be very careful when switching from one MAO inhibitor to another
MAO inhibitors (MAOIs) and contraindicated medications: How long do we have to wait?
How to switch from oral or transdermal selegiline (Emsam®) to another MAO inhibitor
Should we prescribe emergency medication for hypertensive urgency with MAO inhibitors?
“Treatment-resistant” depression: Can a classic MAO inhibitor be safely augmented with an antipsychotic?
Drug interactions with oral contraceptives and intrauterine devices
5 Action Items about OCs and lamotrigine
Does lamotrigine decrease the effectiveness of oral contraceptives?
Change lamotrigine dose in transgender women starting hormonal therapy?
Can oral contraceptives affect clozapine levels?
Don’t cause unwanted pregnancy
Do psychotropic medications affect intrauterine devices (IUDs)?
Drug interactions with tobacco smoking
Smoking can seriously affect some psychotropic medications
Time course of decrease in CYP1A2 activity after smoking cessation
Drug interactions: Miscellaneous
Common and important drug Interactions in psychopharmacology
Think twice before adding topiramate to valproate
Some antidepressants may have clinically important interactions with tramadol (Ultram®)
Important instructions regarding MAO inhibitors and other medications
Why is dextromethorphan being combined with a CYP 2D6 inhibitor?
Switching antidepressants: A difficult case
Important drug interactions between antiretrovirals and antidepressants
Dose adjustment for second-generation antipsychotics based on drug interactions
Drug interactions affecting prodrugs
Tamsulosin (Flomax®) and psychiatric medications: What to watch for
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