Is it true that mirtazapine does not cause hyponatremia?

Over the years, I have heard many colleagues express their belief that, unlike serotonin reuptake inhibitors (SSRIs and SNRIs), mirtazapine does not cause hyponatremia. It is important for us to know whether or not this is true. When a patient develops hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) associated with a…