Below are links to the MANY articles on this website about ANTIPSYCHOTIC MEDICATIONS.
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General topics about antipsychotics
Antibiotics, antipsychotics, and QTc prolongation
Which antipsychotics to prefer in patients with catatonia
Antipsychotics and QTc prolongation
How often should we order ECG (EKG) during treatment with a psychotropic medication?
Can a combination of two second-generation antipsychotics work after one alone did not?
When is it appropriate to combine two antipsychotics?
Avoid these three antipsychotics in women with breast cancer
The patient who “demands” TWO antipsychotics
Clinical case: Add as-needed quetiapine to a full dose of aripiprazole?
Practice guideline: Antipsychotics for agitation/psychosis in dementia
Second-generation (atypical) antipsychotics
Second-generation (“atypical”) antipsychotics (List)
Second-generation antipsychotics: Dose equivalents
Dose adjustment for second-generation antipsychotics based on drug interactions
The patient who “demands” TWO antipsychotics
Aripiprazole (Abilify®)
FDA issues new warning about aripiprazole (impulse control problems)
Aripiprazole (Abilify®): Basic Information
Aripiprazole with sensor (Abilify Mycite®): Basic Information
Can aripiprazole *worsen* psychosis?
How exactly to add aripiprazole for hyperprolactinemia with risperidone
Resolution of hyperglycemia after switching to aripiprazole
What dose of aripiprazole as an adjunct for OCD?
What is the risk of tardive dyskinesia with LOW-dose aripiprazole?
Aripiprazole—Long-acting injectable (LAI) preparations
Aripiprazole (Abilify Maintena®): Basic Information
Aripiprazole lauroxil (Aristada®): Basic Information
Aripiprazole lauroxil (Aristada Initio™): Basic information
Aripiprazole extended-release injectable suspension (Abilify Asimtufii®): Basic Information
Abilify Asimtufii® has two BIG advantages over Abilify Maintena®
Aripiprazole lauroxil (Aristada®) versus Aripiprazole (Abilify Maintena®)
How to convert from oral to long-acting injectable (LAI) aripiprazole
Be careful in converting from Abilify Maintena® to Aristada®
Why does Abilify Maintena® have an FDA indication for bipolar disorder but Aristada® does not?
Asenapine (Saphris®)
Brexpiprazole (Rexulti®)
Brexpiprazole (Rexulti®): Basic Information
Potential side effects of brexpiprazole (Rexulti®)
Brexpiprazole (Rexulti®) for “agitation associated with dementia due to Alzheimer’s disease”
Cariprazine (Vraylar®)
Cariprazine (Vraylar®): Basic Information
Cariprazine (Vraylar): Potential side effects
Activity of cariprazine (Vraylar®) on dopamine D3 and D2 receptors
Cariprazine (Vraylar®): Organized list of references
Clozapine (Clozaril®)
Clozapine—General information
Clozapine (Clozaril®): Basic Information
Why we must refer more patients for clozapine treatment
What can we do about the underutilization of clozapine and delays in starting it?
Where can I find someone who prescribes clozapine?
Clozapine for schizophrenia in children?
Changes in the rules about clozapine
Clozapine—Serum level
How to check and interpret clozapine levels
Are the clozapine-norclozapine ratio and norclozapine level useful?
Can oral contraceptives affect clozapine levels?
Caffeine can significantly change serum clozapine levels
Clozapine—Side effects
Potential side effects of clozapine (Clozaril®) handout
Key information about seizures with clozapine
Clozapine-induced hypersalivation (sialorrhea)
Clozapine-induced hypersalivation (sialorrhea): Treatment
Management of clozapine-induced constipation
Benign ethnic neutropenia (BEN)
Iloperidone (Fanapt®)
Lumateperone (Caplyta®)
Lumateperone (Caplyta®): Basic information
Lumateperone for adjunctive treatment of major depressive disorder
Is lumateperone (Caplyta®) really different from other atypical antipsychotics?
Potential side effects of lumateperone (Caplyta®) handout
Is lumateperone less likely to cause extrapyramidal symptoms (including parkinsonism or akathisia)?
Can lumateperone (Caplyta®) cause metabolic side effects?
Lurasidone (Latuda®)
Lurasidone (Latuda®): Basic Information
Lurasidone (Latuda®): Pharmacological Effects
Lurasidone (Latuda®): Efficacy
Lurasidone (Latuda®): Drug Interactions
Lurasidone (Latuda®): Adverse Effects
What are the possible risks of using lurasidone (Latuda®) during pregnancy
Which psychiatric medications MUST be taken with food?
Does lurasidone (Latuda®) really have a low risk of increasing serum prolactin?
Olanzapine (Zyprexa®)
Olanzapine (Zyprexa®): Basic Information
Does olanzapine (Zyprexa®) really have a low risk of increasing serum prolactin?
Olanzapine—Long-acting injectable (LAI) preparation
Olanzapine (Zyprexa Relprevv®): Basic Information
Extended-Release Olanzapine (Zyprexa Relprevv®): REMS
Olanzapine-Samidorphan (Lybalvi®)
Olanzapine and samidorphan (Lybalvi®): Basic information
Samidorphan versus naltrexone: What’s the difference?
How much better is olanzapine-samidorphan (Lybalvi®) than olanzapine alone? Part 1
Paliperidone (Invega®)
Paliperidone (Invega®): Basic Information
Potential side effects of paliperidone (Invega®): Patient handout
Paliperidone—Long-acting injectable (LAI) preparations
Paliperidone palmitate (Invega Sustenna®): Basic Information
How to convert from oral paliperidone or risperidone to paliperidone palmitate 1-month LAI
Paliperidone palmitate 3-month (Invega Trinza®): Basic Information
Paliperidone palmitate 6-month (Invega Hayfera™): Basic Information
Pimavanserin (Nuplazid®)
Pimavanserin (Nuplazid): Basic Information
What is pimavanserin (Nuplazid®)?
Pimavanserin (Nuplazid®): Potential adverse effects
Quetiapine (Seroquel®)
Quetiapine (Seroquel®, Seroquel XR®): Basic Information
Which psychotropic medications should be taken WITHOUT food?
The dose of quetiapine is NOT the same for each disorder
Is quetiapine (Seroquel®) a reasonable option for treating insomnia?
Why it matters that quetiapine’s metabolite is a *norepinephrine* reuptake inhibitor
Risperidone (Risperdal®)
Risperidone (Risperdal®): Basic Information
News: July 6, 2016. Make sure you are discussing the increased risk of gynecomastia with risperidone
How exactly to add aripiprazole for hyperprolactinemia with risperidone
Risperidone—Long-acting injectable (LAI) preparations
Risperidone long-acting injection (RLAI; Risperdal Consta®): Basic Information
Risperdal Consta® Prescribing Information
Equivalence of risperidone oral and long-acting injection (RLAI; Risperdal Consta®)
How to convert from oral paliperidone or risperidone to paliperidone palmitate 1-month LAI
Ziprasidone (Geodon®)
Long-acting injectable (LAI) antipsychotics: General articles
(For our articles about long-acting injectable preparations of specific antipsychotics, please look under that antipsychotic on this page.)
Long-acting injectable antipsychotics: Overview
Dose equivalents of long-acting injectable second-generation antipsychotics
How *NOT* to offer long-acting injectable (LAI) antipsychotics to patients
Which injections can only be given in the gluteal muscle—and why?
How to choose between injecting into the deltoid or gluteal muscles
CPT billing code for administration of injections
When is it appropriate to combine two antipsychotics?
First-generation (typical) antipsychotics
Antipsychotics—Side effects
Antipsychotics—Metabolic Side Effects
Does weight gain with second-generation (atypical) antipsychotics plateau after the first few months?
How long does antipsychotic-induced hyperglycemia take to resolve?
Resolution of hyperglycemia after switching to aripiprazole
Do adolescents have more metabolic side effects with second-generation antipsychotics?
How to monitor for metabolic side effects in adults on second-generation antipsychotics
How to monitor for metabolic side effects in children and adolescents on a second-generation (atypical) antipsychotic
Why do some antipsychotics carry a warning about suicidal thoughts or actions?
Which antipsychotics are more or less often associated with urinary incontinence or enuresis?
Amantadine for antipsychotic-induced parkinsonism
Amantadine (Symmetrel): Basic Information
Is TD less likely with second-generation (“atypical”) antipsychotics?
Does any atypical antipsychotic have a lower risk of tardive dyskinesia?
Management of tardive dyskinesia: First-line options
Management of tardive dyskinesia: Second-line options
Be careful if a person is on both a stimulant and an antipsychotic
What could happen when changing from an antipsychotic to a stimulant?
Key information about seizures with clozapine
Can we use topiramate to treat medication-induced weight gain?
Potential risks of second-generation (atypical) antipsychotics in pregnancy
Akathisia: Treatment with a beta-blocker
How and why to compare antipsychotics’ affinity for alpha-1 receptors
Antipsychotics—Drug interactions
Smoking and psychotropic medications
Can stimulant and antipsychotic medications be used together?
When a stimulant and an antipsychotic are used together and then the stimulant is stopped
Going from atomoxetine to an antipsychotic
Changing from an antipsychotic to a stimulant
Alpha-2 adrenergic receptor agonists
Off-label treatments for schizophrenia and related psychotic disorders
Cannabidiol for schizophrenia or other psychotic disorders? An overview
What did randomized, double-blind clinical trials of cannabidiol in schizophrenia find?
Does estrogen have a role in schizophrenia?
Estrogen as a treatment for schizophrenia?
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