Risperidone (US brand name Risperdal® and generic) is a second-generation (“atypical”) antipsychotic. Here is basic information about this medication.
FDA-approved indications
1. Treatment of schizophrenia
2. As monotherapy or adjunctive therapy with lithium or valproate, for the treatment of acute manic or mixed episodes associated with Bipolar I Disorder
3. Treatment of irritability associated with autistic disorder
Dosage
Recommended daily dosage:
Schizophrenia (adults)
Initial dose: 2 mg
Target dose: 4–8 mg
Effective dose range: 4–16 mg
Schizophrenia (adolescents)
Initial dose: 0.5 mg
Target dose: 3 mg
Effective dose range: 1–6 mg
Bipolar mania (adults)
Initial dose: 2–3 mg
Target dose: 1–6 mg
Effective dose range: 1–6 mg
Bipolar mania (children and adolescents)
Initial dose: 0.5 mg
Target dose: 1–2.5 mg
Effective dose range: 1–6 mg
Irritability associated with autistic disorder (weight <20 kg)
Initial dose: 0.25 mg
Target dose: 0.5 mg
Effective dose range: 0.5–3 mg
Irritability associated with autistic disorder (weight ≥20 kg)
Initial dose: 0.5 mg
Target dose: 1 mg
Effective dose range: 0.5–3 mg
Dosage forms and strengths
Tablets (Risperdal® and generic): 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg
Oral solution (Risperdal® and generic): 1 mg/mL
Orally disintegrating tablets (Risperdal M-tab® and generic): 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg
Please refer to Prescribing Information (see link below) for a complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
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References
Risperidone Prescribing Information
Copyright 2016, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
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Can you please discuss how to interpret risperidone levels? Serum risperidone, total (risperidone plus 9-OH-risperidone). Thank you.