Long-acting injectable (LAI) or “depot” antipsychotics are important because of the widespread problem of nonadherence to medication.
The second-generation (“atypical”) antipsychotics available in the USA as long-acting injectables are, alphabetically:
-
Aripiprazole monohydrate (Abilify Maintena®)
-
Aripiprazole lauroxil (Aristada®)
-
Aripiprazole lauroxil (Aristada Initio®)—Only for starting or restarting aripiprazole lauroxil (Aristada®)
-
Olanzapine pamoate (Zyprexa Relprevv®)
-
Paliperidone palmitate (Invega Sustenna®)
-
Paliperidone palmitate 3-monthly (Invega Trinza®)
-
Paliperidone palmitate 6-monthly (Invega Hafyera®)
-
Risperidone long-acting injection (Risperdal Consta®)
-
Risperidone long-acting injectable for subcutaneous use (Perseris®)
Related Pages
Dose equivalents of long-acting injectable second-generation antipsychotics
CPT billing code for administration of injections
Aripiprazole (Abilify Maintena®)
Aripiprazole lauroxil (Aristada®)
Aripiprazole lauroxil (Aristada®) versus Aripiprazole (Abilify Maintena®)
Aripiprazole lauroxil (Aristada Initio®)
Be careful in converting from Abilify Maintena® to Aristada®
Olanzapine (Zyprexa Relprevv®)
Paliperidone palmitate (Invega Sustenna®)
Paliperidone palmitate 3-month (Invega Trinza®)
Risperidone long-acting injection (Risperdal Consta®): Basic Information
Equivalence of risperidone oral and long-acting injection (RLAI; Risperdal Consta®)
References
Miyamoto S, Wolfgang Fleischhacker W. The Use of Long-Acting Injectable Antipsychotics in Schizophrenia. Curr Treat Options Psychiatry. 2017;4(2):117-126. Review. PubMed PMID: 28580230; PubMed Central PMCID: PMC5432557.
Khan AY, Salaria S, Ovais M, Ide GD. Depot antipsychotics: Where do we stand? Ann Clin Psychiatry. 2016 Nov;28(4):289-298. PubMed PMID: 27901520.
Citrome L. Aripiprazole long-acting injectable formulations for schizophrenia: aripiprazole monohydrate and aripiprazole lauroxil. Expert Rev Clin Pharmacol. 2016;9(2):169-86. Review. PubMed PMID: 26573020.
Copyright 2017 to 2021, Simple and Practical Medical Education, LLC. All rights reserved. May not be reproduced in any form without express written permission.
Disclaimer: The content on this website is provided as general education for medical professionals. It is not intended or recommended for patients or other laypersons or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.
Leave a Reply: