Aripiprazole with sensor (US brand name Abilify Mycite®) is a drug-device combination consisting of aripiprazole tablets embedded with an Ingestible Event Marker (IEM) sensor for tracking drug ingestion. Here is basic information about this medication.
FDA-approved indications
1. Treatment of adults with schizophrenia
2. Treatment of bipolar I disorder
- Acute treatment of adults with manic and mixed episodes as monotherapy and as adjunct to lithium or valproate
- Maintenance treatment of adults as monotherapy and as adjunct to lithium or valproate
3. Adjunctive treatment of adults with major depressive disorder (MDD)
Dosage
Schizophrenia – adults
Initial Dose: 10-15 mg/day
Recommended Dose: 10-15 mg/day
Maximum Dose: 30 mg/day
Bipolar mania – adults: monotherapy
Initial Dose: 15 mg/day
Recommended Dose: 15 mg/day
Maximum Dose: 30 mg/day
Bipolar mania – adults: adjunct to lithium or valproate
Initial Dose: 10-15 mg/day
Recommended Dose: 15 mg/day
Maximum Dose: 30 mg/day
Major Depressive Disorder – Adults adjunct to antidepressants
Initial Dose: 2-5 mg/day
Recommended dose: 5-10 mg/day M
Maximum dose: 15 mg/day
Instructions
Administer once daily without regard to meals
Swallow whole; do not divide, crush, or chew
Known CYP2D6 poor metabolizers: Administer half of the usual dose
Limitations of use
1. It is not established that aripiprazole with sensor can improve patient compliance or modify aripiprazole dosage
2. Aripiprazole with sensor is not recommended for tracking drug ingestion in real-time or during an emergency because detection may be delayed or not occur
Dosage forms and strengths (USA)
Tablets with sensor: 2 mg, 5 mg, 10 mg, 15 mg, 20 mg, and 30 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Related Pages
FDA issues new warning about aripiprazole (impulse control problems)
Be careful in converting from Abilify Maintena® to Aristada®
Aripiprazole (Abilify Maintena®)
Aripiprazole lauroxil (Aristada®)
References
Prescribing information for aripiprazole with sensor (Abilify Mycite®)
Copyright 2017, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
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