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Why is dextromethorphan combined with a CYP 2D6 inhibitor?

Dextromethorphan is a cough suppressant that also has multiple effects in the central nervous system (CNS) that are of interest to neurologists and mental health clinicians. The CNS effects of dextromethorphan will be discussed on another page on this website.  Dextromethorphan has been combined with quinidine (brand name Nuedexta) because quinidine inhibits the enzyme cytochrome…

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