Mixed amphetamine salts (Adderall® brand has been discontinued but is available as a generic; Adderall XR® brand name and generic) is a formulation of amphetamine that contains amphetamine aspartate, amphetamine sulfate, dextroamphetamine saccharate, and dextroamphetamine sulfate. Here is basic information about this medication.
Mixed Amphetamine Salts (Adderall®)
FDA-approved indications
1. Attention deficit hyperactivity disorder (ADHD)
2. Narcolepsy
Dosage
A. ADHD
Children (ages 3-5)
Initial: 2.5 mg daily
Titration: 2.5 mg weekly increments until clinical response
Children (ages 6 years or older)
Initial: 5 mg once or twice daily
Titration: 5 mg weekly increments until clinical response
Maximum: 40 mg daily in 2-3 divided doses with first dose given on waking up and rest at interval of 4-6 hours
B. Narcolepsy
Children (ages 6-12 years)
Initial: 5 mg daily
Titration: 5 mg weekly increments until clinical response
Children and Adults (≥ 12 years)
Initial: 10 mg daily
Titration: 10 mg weekly increments until clinical response. Reduce dosage in case of adverse effects.
May be given in 2-3 divided doses with first dose given on waking up and rest at interval of 4-6 hours.
Dosage forms and strengths
Tablets (generic): 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, and 30 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Mixed Amphetamine Salts Extended-Release (Adderall XR®)
FDA-approved indications
Treatment of ADHD in children, adolescents, and adults
Dosage
Children (ages 6-12)
Initial: 10 mg once daily in the morning
Titration: 5 mg or 10 mg weekly increments
Maximum: 30 mg once daily in the morning
Adolescents(ages 13-17)
Initial: 10 mg once daily in the morning
Increase to 20 mg after 1 week
Adults
20 mg once daily in the morning
Note: Capsules may be opened and contents may be sprinkled over applesauce and consumed immediately.
Dosage forms and strengths
Extended-release capsules: 5 mg, 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Related Pages
Amphetamine Preparations (Free)
Does lisdexamfetamine really have lower abuse potential?
Converting stimulants: Equivalent doses
References
Mixed salts of amphetamine (Adderall®) Prescribing Information
Mixed salts of amphetamine extended-release (Adderall XR®) Prescribing Information
Copyright 2016, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
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