Amphetamine extended-release orally disintegrating tablets (Adzenys XR-ODT): Basic Information

Amphetamine extended-release orally disintegrating tablet (Adzenys XR-ODT™) is a central nervous stimulant. Here is basic information about this medication.

Adzenys XR-ODT tablets are made up of microparticles containing amphetamine. Half of the dose is contained in microparticles of immediate-release amphetamine. The other half of the dose is contained in extended-release microparticles.

FDA-approved indications

Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older

Dosage

Pediatric (6-17 years)

Starting: 6.3 mg once daily in the morning

Titration: Increase in increments of 3.1 mg or 6.3 mg at weekly intervals

Maximum: 18.8 mg once daily (6-12 years) and 12.5 mg once daily (13-17 years)

Adults

Recommended: 12.5 mg daily

Dosing considerations

• May be taken with or without food
• Tablet should remain in the blister pack until the patient is ready to take it.
• The patient or caregiver should use dry hands to open the blister.
• Tear along the perforation, bend the blister where indicated and peel back the blister’s labeled backing to take out the tablet. The tablet should not be pushed through the foil.
• As soon as the blister is opened, the tablet should be removed and placed on the patient’s tongue.
• The whole tablet should be placed on the tongue and allowed to disintegrate without chewing or crushing.
• The tablet will disintegrate in saliva so that it can be swallowed

Switching from Other Amphetamine Products

Patients taking Adderall XR may be switched to Adzenys XR-ODT at the equivalent dose taken once daily (see table below)

[table id=1 /] If switching from any other amphetamine products discontinue that treatment and titrate with Adzenys XR-ODT using the titration schedule

Dosage forms and strengths

Orally disintegrating tablets: 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, and 18.8 mg

Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.

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Related Pages

Amphetamine preparations

Stimulants: Main page (links to all pages on this topic)

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References

Adzenys XR-ODT Prescribing Information

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