Amphetamine extended-release orally disintegrating tablet (Adzenys XR-ODT™) is a central nervous stimulant. Here is basic information about this medication.
Adzenys XR-ODT tablets are made up of microparticles containing amphetamine. Half of the dose is contained in microparticles of immediate-release amphetamine. The other half of the dose is contained in extended-release microparticles.
FDA-approved indications
Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older
Dosage
Pediatric (6-17 years)
Starting: 6.3 mg once daily in the morning
Titration: Increase in increments of 3.1 mg or 6.3 mg at weekly intervals
Maximum: 18.8 mg once daily (6-12 years) and 12.5 mg once daily (13-17 years)
Adults
Recommended: 12.5 mg daily
Dosing considerations
- May be taken with or without food
- Tablet should remain in the blister pack until the patient is ready to take it.
- The patient or caregiver should use dry hands to open the blister.
- Tear along the perforation, bend the blister where indicated and peel back the blister’s labeled backing to take out the tablet. The tablet should not be pushed through the foil.
- As soon as the blister is opened, the tablet should be removed and placed on the patient’s tongue.
- The whole tablet should be placed on the tongue and allowed to disintegrate without chewing or crushing.
- The tablet will disintegrate in saliva so that it can be swallowed
Switching from Other Amphetamine Products
Patients taking Adderall XR may be switched to Adzenys XR-ODT at the equivalent dose taken once daily (see table below)
Equivalent Doses of Adzenys XR-ODT and Adderall XR
| Adzenys XR-ODT™ | 3.1 mg | 6.3 mg | 9.4 mg | 12.5 mg | 15.7 mg | 18.8 mg |
| Adderall XR® | 5 mg | 10 mg | 15 mg | 20 mg | 25 mg | 30 mg |
Dosage forms and strengths
Orally disintegrating tablets: 3.1 mg, 6.3 mg, 9.4 mg, 12.5 mg, 15.7 mg, and 18.8 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Related Pages
Amphetamine preparations
Stimulants: Main page (links to all pages on this topic)
References
Adzenys XR-ODT Prescribing Information
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