Many, but not all, antidepressants are available as liquid formulations, which include oral solutions or oral concentrates. These are useful in many situations—for children, those with trouble swallowing, when fine titration is required, and so on.
The following are the liquid preparations of antidepressants that are available in the US as of May 2022.
Citalopram (generic) 10 mg/5 mL (150 mL, 200 mL, 225 mL, 240 mL, 300 mL)
Escitalopram oral solution (generic) 5 mg/5 mL (150 mL, 240 mL, 300 mL, 450 mL, 600 mL). The escitalopram oral solution may be mixed with other liquids like water, orange juice, or apple juice (source).
Fluoxetine (generic) 20 mg/5 mL (120 mL)
Paroxetine (generic) 10 mg/5mL (250 mL)
Sertraline (generic) 20 mg/mL (60 mL). Note: Sertraline is available as an “oral concentrate”, which is not the same as an oral solution. Sertraline oral concentrate contains 20 mg per mL and it must be diluted before it is taken.
Fluvoxamine (not available as a liquid)
None of them is available as a liquid (desvenlafaxine ER, duloxetine, levomilnacipran, milnacipran, venlafaxine/venlafaxine ER).
Nortriptyline 10 mg/5 mL (75 mL, 115 mL, 150 mL, 300 mL, 473 mL)
None of them is available as a liquid (phenelzine, tranylcypromine, isocarboxazid).
Bupropion/ bupropion SR/ bupropion XL—not available as a liquid
Mirtazapine—not available as a liquid
SSRIs: As of May 2022, liquid formulations are available in the US for all but one of the six SSRIs—for citalopram, escitalopram, fluoxetine, paroxetine, and sertraline, but not for fluvoxamine.
TCAs: A liquid formulation is available for nortriptyline.
Other antidepressants: A liquid formulation is NOT available for any of the serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants other than nortriptyline, or any of the MAO inhibitors.
Medication formulations and their contents
Medication cost, generics, pharmacies
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