Suvorexant (Belsomra®) is an orexin receptor antagonist that is used as a hypnotic. Here is basic information about this medication.
Treatment of insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance.
Suvorexant is an orexin receptor antagonist and is the first approved drug that works through this mechanism. Orexins in the brain are involved in regulating the sleep-wake cycle and wakefulness.
Start with the lowest effective dose in adults.
Recommended: 10 mg, given within 30 minutes of going to bed, with at least 7 hours remaining till planned awakening.
Maximum: 20 mg (if needed and tolerated)
i: Effect may be delayed if taken with or within 30 minutes after food.
Potential side effects
Other: diarrhea, dry mouth, upper respiratory tract infections, abnormal dreams, cough.
Please see THIS PAGE for a handout listing both the common and less common side effects of this medication along with the percentages of patients who report them.
Dosage forms and strengths
Tablets: 5 mg, 10 mg, 15 mg, 20 mg
Important! Please refer to the full Prescribing Information (see the link below) before prescribing this medication.
Orexin receptor antagonists
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