Symbyax® (brand name and generic) is a combination of olanzapine, an atypical antipsychotic and fluoxetine, a selective serotonin reuptake inhibitor (an antidepressant). Here is basic information about this medication.
FDA-approved indications
Acute depressive episodes associated with bipolar I disorder and treatment resistant depression
Treatment resistant depression
Dosage
Depressive episodes associated with bipolar I disorder (adults)
Starting dose: 6 mg olanzapine and 25 mg fluoxetine (6 mg/25 mg) once daily in the evening
Maximum dose: 12 mg olanzapine and 50 mg fluoxetine (12 mg/50 mg) once daily in the evening
Depressive episodes associated with bipolar I disorder (children and adolescents 10-17 years old)
Starting dose: 3 mg olanzapine and 25 mg fluoxetine (3 mg/25 mg)
Maximum dose: 12 mg olanzapine and 50 mg fluoxetine (12 mg/50 mg)
Treatment resistant depression
Starting dose: 6 mg olanzapine and 25 mg fluoxetine (6 mg/25 mg) once daily in the evening
Maximum dose: 18 mg olanzapine and 50 mg fluoxetine (18 mg/50 mg) once daily in the evening
Dosage forms and strengths
Capsules: 3 mg/25 mg, 6 mg/25 mg, 6 mg/50 mg, 12 mg/25 mg, and 12 mg/50 mg (mg olanzapine/mg equivalent fluoxetine)
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Related Pages
Prescribing information for Symbyax®
Which antidepressants for bipolar depression
Olanzapine (Zyprexa®): Basic Information
Fluoxetine (Prozac®): Basic information
Copyright 2018, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
Disclaimer: The content on this website is provided as general education for medical professionals. It is not intended or recommended for patients or other laypersons, or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.
Leave a Reply: