Isocarboxazid (Marplan®) is a non-selective hydrazine monoamine oxidase (MAO) inhibitor. Here is key information about this medication.
Starting: 20 mg/day (in two divided doses)
End of 1st week: 40 mg/day
Maximum: 60 mg/day in 2-4 divided doses
After the starting dose, further increase may be in increments of 10 mg every 2-4 days to 40 mg at the end of first week, and then 20 mg/week until maximum of 60 mg/day, if needed and tolerated.
Once the maximal therapeutic response is achieved, an attempt should be made to decrease the dosage to the lowest effective level, over several weeks.
Avoid tyramine rich foods or beverages, in combination with isocarboxazid, or within two weeks after stopping treatment.
Dose forms and strengths
Tablets: 10 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
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