This article was published on April 21, 2022
Modafinil (Provigil®)
Modafinil has an FDA indication “to improve wakefulness in adult patients excessive sleepiness associated with narcolepsy, obstructive sleep apnea (OSA), or shift work disorder (SWD)”.
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Armodafinil (Nuvigil®)
Armodafinil has an FDA indication “to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD)”.
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Solriamfetol (Sunosi®)
A dopamine and norepinephrine reuptake inhibitor (DNRI) with an FDA indication “to improve wakefulness in adult patients with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea (OSA)”.
Pitolisant (Wakix®)
A histamine-3 (H3) receptor antagonist/inverse agonist with an FDA indication “for the treatment of excessive daytime sleepiness (EDS) or cataplexy in adult patients with narcolepsy“.
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