by Vivien K Burt, MD, Ph.D. (Bio)
Professor Emeritus of Psychiatry,
The David Geffen School of Medicine at UCLA.
Founder and Co-Director
The Women’s Life Center
Resnick UCLA Neuropsychiatric Hospital
Los Angeles, California
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Copyright 2019, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
Disclaimer: The content on this website is provided as general education for medical professionals. It is not intended or recommended for patients or other lay persons or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.
Question from a Member:
How much higher would the risk of blood clots be if hormones were prescribed to a female patient on clozapine who
Before prescribing hormone therapy in peri- and postmenopausal women, the potential risks with the patient’s gynecologist and primary care doctor. But, mental health clinicians need at least a basic understanding of the risks so that we can consider them in making our recommendations.
Here is a brief summary of the potential risks of hormone therapy in peri- and postmenopausal women :
1. Coronary heart disease: Hormone therapy has a harmful effect on coronary heart disease in older women and in women with a higher increased risk for coronary heart disease.
2. Breast cancer: Combined estrogen and progestin therapy increases the risk of breast cancer.
3. Other risks: Overall, women on either combined hormonal therapy or estrogen alone had more strokes, blood clots, gall bladder disease, and urinary incontinence.
Role of smoking: Though smoking is not a contraindication for hormone therapy, it is a major independent risk factor for cardiovascular disease. So, the risk of cardiovascular disease in older women being considered for hormone therapy is greater in women who smoke.
Bottom line: For women with a history of blood clots, heart disease, stroke, or breast cancer, hormone therapy may not be prudent.
Related Pages
Copyright 2019, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
Disclaimer: The content on this website is provided as general education for medical professionals. It is not intended or recommended for patients or other lay persons or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.
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