Vilazodone (Viibryd®): What drug interactions should we look out for?

What drug-drug interactions can vilazodone cause? Vilazodone can affect other drugs through two mechanisms: – Like many other antidepressants, vilazodone is 98% protein-bound and therefore it may displace other drugs that are highly protein-bound, for example, digoxin, aspirin, and warfarin. The free fraction of these drugs could be increased, leading to an increased effect of…