What is VMAT2 and what do VMAT2 inhibitors do?

Deutetrabenazine (Austedo®) and valbenazine (Ingrezza®) are selective inhibitors of vesicular monoamine transporter 2 (VMAT2). They have been approved by the United States FDA for the treatment of adults with tardive dyskinesia, the first medications ever to be FDA-approved for this indication. What is VMAT2? VMAT2 sounds like the name of a rocket, I know. But…