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How to differentiate substance/medication-induced bipolar disorder from bipolar I or II disorder

  A Member asked about a patient who was treated on two occasions with an SSRI and on both occasions, he manifested what appears to be “substance/medication-induced bipolar” behavior—staying up all night, indiscriminate destruction of property within the family home, and high energy oppositional/defiant behavior. The DSM-5-TR has a diagnostic category called “Substance/Medication-Induced Bipolar and Related Disorder” (American Psychiatric…

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