Are there clinically-important differences between the various SNRIs?

Question from a Member: Clinically, what are the pros and cons of venlafaxine vs duloxetine? This is a clinically relevant question—Are all the SNRIs quite similar to each other or are there clinically-important differences between them? There are five SNRIs that are available in the US. They are (alphabetically): – Desvenlafaxine (Pristiq®) – Duloxetine (Cymbalta®)…