A primer on serotonin receptors

Negative feedback of serotonin release Serotonin release in the brain is controlled in part by multiple negative feedback loops. When a serotonin reuptake inhibitor is started and serotonin release increases, these negative feedback loops immediately come into play and reduce the serotonin release, at least initially. These negative feedback loops are: 1. Serotonin 1A receptors:…