Why it matters that quetiapine’s metabolite is a *norepinephrine* reuptake inhibitor

Two of our Members posted related questions about whether quetiapine is also an inhibitor of serotonin or norepinephrine reuptake. They pointed out that such an effect could have clinically relevant implications for the safety of using quetiapine along with some other medications, for example, monoamine oxidase (MAO) inhibitors. Norquetiapine and its pharmacological effects – Is…