Pharmacogenetics and the risk of antidepressant-induced switching to mania or hypomania

Question from a Member: What is the evidence that someone with SLC6A4 L(G)/S [low activity] would be more or less prone to bipolar switching? First, let’s digest our Member’s question For more on the genetic variations related to the gene that codes for the serotonin transporter and their clinical significance, please see the following article…