Ondansetron (Zofran®), QT prolongation, and psychotropic medications

By Rajnish Mago, MD (bio) Question from a Member: Your recent recommendations for the treatment of medication-induced nausea reminded me of a question I had. Epocrates® indicates that ondansetron (brand name Zofran) is contraindicated with SSRI’s and SNRI’s due to concern about serotonin syndrome and QT prolongation. It would seem to me that the former…