MAO inhibitor-induced insomnia

MAO inhibitors can lead to a feeling of being overstimulated during the day and to insomnia at night. While daytime hyperstimulation may be more likely to occur with tranylcypromine, insomnia occurs with both phenelzine and tranylcypromine (Remick et al., 1989). What can we do? 1. Recommend taking more of the medication earlier in the day rather…