Levomilnacipran (Fetzima®): Drug Interactions

What are potential drug-drug interactions with levomilnacipran?  Two facts about levomilnacipran are relevant here: a) Levomilnacipran is not a significant inducer or inhibitor of any cytochrome P450 isoenzyme. b) 58% of the dosage is excreted unchanged in urine. Because of these two reasons: P450 drug interactions in either direction are less likely with levomilnacipran. That…