Is mirtazapine less sedating at higher doses?

This article was first published on July 24, 2018. It was last reviewed, updated, or edited on July 25, 2024. It has been hypothesized that mirtazapine may be less sedating at doses of 30 mg/day or more compared to doses of 15 mg or less. This belief has become widespread–among patients, prescribing clinicians, and authors of…