Direct-acting oral anticoagulants (DOACs) and antidepressants

Question from a Member: I have a 42-year-old obese, depressed female with numerous medical conditions: antiphospholipid antibody syndrome (diagnosed after a pulmonary embolus), hypertension, diabetes type 2. She takes rivaroxaban (brand name Xarelto), amlodipine, carvedilol, dulaglutide (brand name Trulicity), and insulin. What antidepressant would you recommend? DISCLAIMER! We cannot give medical advice about a particular…