Clinical case: Valproate toxicity despite a valproic acid level in the usual therapeutic range

This article was first published on July 8, 2023. It was last reviewed/ updated on July 9, 2023. One of my outpatients with bipolar disorder and ADHD is being treated with divalproex extended-release (Depakote ER®), along with lurasidone, atomoxetine, and gabapentin. He was smoking natural cannabis intermittently and I was trying to get him to…