Can mirtazapine be started at 30 mg per day?

Question from a Member: Is it sometimes reasonable to start mirtazapine at 30 mg daily? Any research evidence for this? The recommended starting dose for mirtazapine (brand name Remeron) is 15 mg once daily (Prescribing Information). But… 1. Some clinical trials of mirtazapine started patients on 30 mg/day on day one (e.g., Bleier et al.,…