This article was first published on January 24, 2024. It was last reviewed, updated, or edited on January 24, 2024. The CAGE questionnaire has been used for many decades as a screening tool for “alcoholism”. The letters C.A.G.E. stand for Cutting down, Annoyance by criticism, Guilty feeling, and Eye-openers (Ewing, 1984). The acronym CAGE was…