Bupropion for panic disorder?

Serotonergic antidepressants, especially SSRIs, are the main medications we prescribe for panic disorder. What about bupropion? As we all know, bupropion is not the best choice for a patient with panic disorder. Why? 1. The only randomized controlled trial of this that I am aware of was single-blind and had only 13 patients (Sheehan et…