What to tell patients with alcohol use disorder about taking acetaminophen (paracetamol)

Do you proactively say anything to your patients with alcohol use disorder about taking acetaminophen (called paracetamol in other countries) for pain or fever? Here are some key facts about this: 1. Chronic, excessive use of alcohol leads to the induction of a cytochrome P450 enzyme in the liver called CYP2E1 (Woreta and Alqahtani, 2014)….