Can patients with ADHD develop a tolerance to stimulant medications?

This article was first published on February 15, 2024. It was last reviewed, updated, or edited on February 16, 2024. Patients with attention-deficit/ hyperactivity disorder (ADHD) sometimes report that the same psychostimulant medication that was initially helpful for their symptoms seems to not be as helpful now. That is, “tolerance” seems to have developed. Could…