FDA-indications
Overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.Dosage and Administration
Trospium should be taken with water on an empty stomach, at least one hour before a meal. The usual dose is 20 mg twice daily but:- If the patient has severe renal impairment (creatinine clearance < 30 mL/min), 20 mg once daily at bedtime.
- For patients 75 years or older, the dose may be decreased to 20 mg once daily if needed.
Dosage forms and Strengths
Tablets: 20 mgContraindications
– Urinary retention – Gastric retention – Uncontrolled narrow-angle glaucoma Also, patients who are at risk for the conditions listed above. And, obviously, patients with known hypersensitivity.Warnings and Precautions
Trospium should be used with caution in patients with clinically significant: – Bladder outflow obstruction (due to risk of urinary retention) – Gastrointestinal obstructive disorders (due to risk of gastric retention)Side effects
In clinical trials, the most common side effects of troposium were: – Dry mouth 20% – Constipation 10% – Headache 4%Important! Please refer to the full Prescribing Information (see link below) before prescribing this medication.
Related Pages
Anticholinergic medications in mental health: Menu of options
Clinically important differences between the available anticholinergic medications
Side effects: Main menu (index and links)
References
Sanctura® Prescribing Information. Available at https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021595s009lbl.pdf. Accessed June 16, 2022.Copyright © 2022, Simple and Practical Medical Education, LLC. All rights reserved. May not be reproduced in any form without express written permission. Disclaimer: The content on this website is provided as general education for medical professionals. It is not intended or recommended for patients or other laypersons or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.
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