Trazodone (US brand name Desyrel® which has been discontinued and generic) is an antidepressant that exerts its action by potentiating serotonergic activity in the central nervous system. Here is basic information about this medication.
FDA-approved indications
Major depressive disorder in adults
Dosage
Starting: 150 mg/day in divided doses
Titration: Increase by 50 mg per day every three to four days
Maximum: 400 mg/day in divided doses
Directions
Trazodone hydrochloride tablets should be taken shortly after a meal or light snack.
Tablets should be swallowed whole or broken in half along the score line, and should not be chewed or crushed.
When discontinued, gradual dose reduction is recommended.
Dosage forms and strengths
Oral Tablets (scored, bisect): 50 mg and 100 mg
Oral Tablets (scored, full bisect and 2 partial trisects): 150 mg and 300 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Related Pages
Trazodone and priaprism
Antidepressants: Index and Links
References
Prescribing information for trazodone
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