Trazodone (US brand name Desyrel® which has been discontinued and generic) is an antidepressant that exerts its action by potentiating serotonergic activity in the central nervous system. Here is basic information about this medication.
Major depressive disorder in adults
Starting: 150 mg/day in divided doses
Titration: Increase by 50 mg per day every three to four days
Maximum: 400 mg/day in divided doses
Trazodone hydrochloride tablets should be taken shortly after a meal or light snack.
Tablets should be swallowed whole or broken in half along the score line, and should not be chewed or crushed.
When discontinued, gradual dose reduction is recommended.
Dosage forms and strengths
Oral Tablets (scored, bisect): 50 mg and 100 mg
Oral Tablets (scored, full bisect and 2 partial trisects): 150 mg and 300 mg
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
Copyright 2016, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
Disclaimer: The content on this website is provided as general education for medical professionals.It is not intended or recommended for patients or other laypersons, or as a substitute for medical advice, diagnosis, or treatment. Patients must always consult a qualified health care professional regarding their diagnosis and treatment. Healthcare professionals should always check this website for the most recently updated information.