Lamotrigine is one of the important medications for the treatment of bipolar disorder. However, there are some important details that we need to know about its use.
Does lamotrigine not work for anything acutely?
Is there important unpublished data about lamotrigine that might alter what we think about its efficacy?
Are we increasing the risk of Stevens-Johnson Syndrome by following the FDA-approved titration schedule for lamotrigine?
What clinical conditions increase risk of Stevens-Johnson Syndrome and suggest that lamotrigine should be avoided if possible?
What important detail must be included when documenting that we told the patient about the risk of Stevens-Johnson syndrome?
What should we do if the patient develops a rash?
These questions are addressed by S. Nassir Ghaemi, MD, MPH, Professor of Psychiatry and Director of the Mood Disorders Program at Tufts University School of Medicine in the interview below. Dr. Ghaemi is also Editor of The Psychiatry Letter, a monthly newsletter described as “The monthly source for independent-minded, scientifically-sound practice.”
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Prescribing Information: Lamotrigine (Lamictal®) (External link)
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