Three dual orexin receptor antagonists (DORAs)—daridorexant, lemborexant, and suvorexant—are FDA-approved as hypnotics. They are not my top choice among the options for hypnotic medications, but when we do want to prescribe one of the DORAs, which one should we prescribe? How do we choose among them?
In other articles on this website, we have discussed the dual orexin receptor antagonists (DORAs)— daridorexant, lemborexant, and suvorexant. Please see:
What is the orexin system, and why is it so important?
An overview of dual orexin receptor antagonists (DORAs)
Potential side effects of dual orexin receptor antagonists (DORAs)
Do dual orexin receptor antagonists (DORAs) have a low risk of abuse or dependence?
Are dual orexin receptor antagonists (DORAs) safe in obstructive sleep apnea?
Daridorexant (Quviviq®): Basic information
Lemborexant (Dayvigo®): Basic information
Suvorexant (Belsomra®): Basic information
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