When is it appropriate to combine two antipsychotics?

  In another article on this website, we noted that two oral (non-clozapine) second-generation antipsychotics have not been shown to be more efficacious for the treatment of schizophrenia than monotherapy (in full dose) with one of them. Please see: Can a combination of two second-generation antipsychotics work after one alone did not? But there ARE…