Can a combination of two second-generation antipsychotics work after one alone did not?

This article was first published on May 7, 2023. It was last reviewed/ updated on May `0, 2023. In as many as a quarter to one-third of patients with schizophrenia, antipsychotic medications (other than clozapine) don’t work or don’t work well (Lähteenvuo and Tiihonen, 2021; Potkin et al., 2020). So, it is not surprising that…