“Treatment-resistant” depression: Can a classic MAO inhibitor be safely augmented with an antipsychotic?

This article was first published on December 24, 2022. It was last reviewed and updated on December 24, 2022. Question from a Member: Can an MAO inhibitor be augmented with aripiprazole or brexpiprazole in treatment-resistant depression? I have a patient who quit responding to phenelzine. Why this is a clinically-important question As you know, in…