Don’t withhold antipsychotic augmentation in MDD for the wrong reason

As all our Members know, in all too many patients, the conventional antidepressants we prescribe (SSRIs, SNRIs, bupropion) do not lead to an adequate response despite an adequate dose and duration of treatment. These patients who have had an “inadequate response” to treatment with a conventional antidepressant fall into two groups based on how much…