Levomilnacipran (Fetzima®): Pharmacokinetics

1. Food does not interfere with the absorption and bioavailability of levomilnacipran. That’s good. 2. Plasma protein binding of levomilnacipran is low (27%). Therefore, it is less likely to displace other drugs bound to plasma proteins. That too is good. 3. Metabolism: About 58% of the dosage of levomilnacipran is excreted unchanged in urine. Therefore,…