Dextroamphetamine (US brand name Dexedrine® and generic) is a noncatecholamine, sympathomimetic amine with CNS stimulant activity. Here is basic information about this medication.
FDA-approved indications
Narcolepsy
Attention deficit disorders with hyperactivity
Dosage
A. Narcolepsy
Usual dose is 5–60 mg/day
1. Ages 6-12
Starting: 5 mg daily
Titration: Increments of 5 mg weekly until optimal response
2. Ages 12 and above
Starting: 10 mg daily
Titration: Increments of 10 mg weekly until optimal response
B. Attention deficit disorder with hyperactivity
1. In children ages 3-5
Starting: 2.5 mg daily
Titration: Increments of 2.5 mg weekly until optimal response
2. In children ages 6 and older
Starting: 5 mg once or twice daily
Titration: Increments of 5 mg weekly until optimal response
Maximum: 40 mg daily
Not recommended for children under 3 years of age.
Prescribing instructions
Spansule capsules may be used for once-a-day dosage wherever appropriate. Spansule sustained release capsule releases initial dose promptly while releasing the remaining medication gradually over a prolonged period.
With tablets, give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.
Dosage forms and strengths
Spansule capsules (Dexedrine® and generic): 5 mg, 10 mg, and 15 mg
Tablets (generic) : 2.5 mg, 5 mg (scored), 7.5 mg, 10 mg ( double scored), 15 mg, 20 mg, and 30 mg
Oral Solution (generic): 5 mg/5 mL
Please refer to Prescribing Information (see link below) for complete discussion of dosage, administration, warnings and precautions, contraindications, etc.
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References
Dextroamphetamine Sulfate (Dexedrine®) Prescribing Information
Copyright 2016, Rajnish Mago, MD. All rights reserved. May not be reproduced in any form without express written permission.
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